Advantage Multi (imidacloprid-10%; moxidectin-2.5%) combines 100 percent prevention for heartworm disease, as shown in clinical trials, with the flea control of Advantage, and the treatment and control of intestinal worms (hookworms, roundworms and whipworms). All in one, convenient, monthly topical solution. The convenient Remind Me system sends one dose of the medication out each month to keep your pet’s treatment on schedule.