Denosyl tablets are recommended to improve glutathione levels to help maintain and protect liver function. When liver function is compromised, the exact cause can often be difficult to determine. Support of the liver, regardless of the cause, is essential to improve liver function. Denosyl contains glutathione, a potent antioxidant, which has been shown to protect hepatic cells in the liver of dogs and cats. Denosyl also contains S-Adenosylmethionine (SAMe) which may help repair and regenerate liver cells.

For optimal absorption, tablets should be given on an empty stomach, at least one hour before feeding, as the presence of food decreases the absorption of SAMe. When giving more than one tablet, the total daily dose may be provided as a morning and evening dose. (For example, a daily dose of three tablets could be divided into two tablets in the morning and one tablet in the evening.)